I'm soon going to start running DCU rpg for a group of friends and wondered if
there was anything I need to bear in mind or any specific system related tips
you'd offer.

I'm an experienced GM (I've been running games for about twenty-five years now)
and have played or run most of the super-hero games out there (all three Marvel
rpgs, Mayfair's DC system, GURPS supers, Palladium's Heros Inc., Aberrant etc)
but until now I've not run or played DCU.

Any thoughts or advice?